1 in 8 Cancer Cases Worldwide Are Linked to Infections

Around 2.3 million new cancer cases worldwide in 2024 were linked to infections, equal to regarding 12% of all cancer cases, according to a study published in The Lancet Oncology.

Key points

• East Asia had the largest number, with around 990, 000 cases, or 42% of the global total.
• Pylori caused regarding 760, 000 cancer cases, or 4% of all cases worldwide.
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• Rates were additionally higher than the global average in sub-Saharan Africa, Central and Eastern Europe, and Southeast Asia.
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Most of these cases were linked to Helicobacter pylori, human papillomavirus (HPV), hepatitis B and C viruses, and Epstein-Barr virus (EBV).

Researchers remarked numerous infection-related cancers could be prevented through vaccination, testing and treatment. Five Infections Cause Most Cases.

Notably, the study estimated that H. Pylori caused regarding 760, 000 cancer cases, or 4% of all cases worldwide.

HPV was linked to regarding 750, 000 cases, additionally around 4%, followed by hepatitis B with 360, 000 cases, EBV with 260, 000 cases, and hepatitis C with 160, 000 cases.

David Greenberg of Hackensack Meridian Jersey Shore University Medical Center remarked the findings show that a substantial part of the global cancer burden could be prevented by better controlling infections. New Pill Could Reduce Cholesterol Among Millions of Pakistanis. How These Infections Can Cause Cancer.

HPV is a common sexually transmitted infection and can cause cervical, anal, genital, mouth and throat cancers. A vaccine can prevent HPV and works best when given before a person becomes sexually active.

Chronic hepatitis B and hepatitis C can damage the liver and lead to cirrhosis and liver cancer. Although treatment usually does not cure the infection, hepatitis B can be prevented with a vaccine and treated with antiviral medicines.

There is no vaccine for hepatitis C, but more than 90% of patients can be cured with direct-acting antiviral medicines taken for two or three months.

H. Pylori is the most common bacterial cause of cancer. It can cause stomach ulcers and may lead to stomach cancer, a rare type of lymphoma and possibly colorectal cancer.

In practice, the bacterium spreads through saliva and contaminated food or water and is more common in lower-income countries. Most infections happen during childhood. Doctors can treat it with antibiotics and medicines that reduce stomach acid.

EBV is a common herpesvirus that causes mononucleosis. It stays in the body and can contribute to nasopharyngeal cancer, some lymphomas and stomach cancer.

More than 90% of adults show signs of previous EBV infection. There is at present no vaccine or approved antiviral treatment for it.

Notably, the study additionally included HIV. It is classified as a cancer-causing virus.

Individuals with advanced HIV can develop AIDS-related cancers such as Kaposi sarcoma and non-Hodgkin lymphoma. Even individuals whose HIV is well controlled with treatment still have a higher risk of a number of cancers.

Kaposi-sarcoma-associated herpesvirus, additionally known as HHV-8, usually causes no illness in healthy residents but can cause tumors in individuals with weakened immune systems.

Other infections included in the study were human T-cell lymphotropic virus, Merkel cell polyomavirus, Schistosoma haematobium, and the liver flukes Opisthorchis viverrini and Clonorchis sinensis.

These infections can cause cancers including bladder, liver and bile duct cancer.

Pakistan Reveals When Its First Ever Rover Will Land on the Moon. Lower-Income Countries Carry Most of the Burden.

More than three-quarters of infection-related cancer cases occurred in low- and middle-income countries.

Rates were additionally higher than the global average in sub-Saharan Africa, Central and Eastern Europe, and Southeast Asia. Prevention Could Reduce Cancer Cases. The researchers remarked better infection control could prevent numerous cancer cases.

They highlighted HPV and hepatitis B vaccination, testing and treatment for HIV, H. Pylori, hepatitis B and hepatitis C, safer injection practices, access to condoms and HIV PrEP, and screening for precancerous cervical and anal changes linked to HPV.

For context, the researchers additionally stated more investment is needed to develop new prevention tools, especially for EBV. Stay Connected with ProPakistani.

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