Questions remain as details keep emerging in Hayden Panettiere death

Questions remain as details keep emerging in Hayden Panettiere death.

Key points

• Contributing: Terry Benjamin II, Greenville News; Brendan Morrow, Sameen Chaudhry, KiMi Robinson, USA TODAY.
• Panettiere died from the "toxic effects of fentanyl, 4-ANPP, Alprazolam, Methocarbamol and Quetiapine, " according to a Greenville County Coroner's Office release.
• Panettiere's on-and-off boyfriend Brian Hickerson and his brother, Zach Hickerson, were on the scene and called 911 when the actress went into cardiac arrest.
• Brian Hickerson informed investigators that the couple had arrived in South Carolina the night before, according to the Greenville County investigative report obtained by Greenville News.
• He was published the after day after paying a $150 fine on Sept.

As more details continue to emerge in the death investigation of actress Hayden Panettiere, some questions still remain.

In practice, the "Heroes" and "Nashville" star, 36, died Aug. 16 at an apartment complex in Greenville, South Carolina, from the "toxic effects of fentanyl" and other drugs, according to a release from the Greenville County Coroner's Office. An investigative report afterwards disclosed fentanyl-laced pills and an unidentified white powder were discovered with the former child star when she died.

As investigators reveal more details regarding the circumstances surrounding Panettiere's death, here's what we know and are looking out for as the investigation continues, now. Hayden Panettiere's cause of death included 4-ANPP, methocarbamol.

Panettiere died from the "toxic effects of fentanyl, 4-ANPP, Alprazolam, Methocarbamol and Quetiapine, " according to a Greenville County Coroner's Office release. Fentanyl is a synthetic opioid drug that is applied to relieve pain and is around 100 times more potent than morphine and 50 times more potent than heroin as an anesthetic, according to the Drug Enforcement Administration.

Meanwhile, the "manner of death has been ruled accident, " and no signs of trauma were discovered that would have contributed to Panettiere's death, the release continued. Hayden Panettiere death investigation reveals other drugs discovered with star.

At the scene of her fatal overdose, authorities discovered a bottle of Adderall as well as blue pressed pills and a cut straw that tested positive for fentanyl inside Panettiere's makeup bag, according to the USA TODAY Network's Greenville News. It obtained the investigative report from the Greenville County Medical Examiner.

Other prescription bottles were additionally identified on the kitchen table, and glass vials and prefilled and empty syringes were discovered in a small lunchbox inside the refrigerator, the report remarked.

For context, the investigative report additionally shared that unidentified white powder in a small, clear plastic bag was identified inside a sunglasses case packed in the actress' suitcase. It was not immediately clear whether the white powder discovered in her suitcase was tested or identified, the report went on. Hayden Panettiere death investigation reveals drugs discovered with star: Report.

What Brian Hickerson informed investigators on the scene after Hayden Panettiere's death.

Panettiere's on-and-off boyfriend Brian Hickerson and his brother, Zach Hickerson, were on the scene and called 911 when the actress went into cardiac arrest. Now, investigators are revealing what Hickerson informed them after her fatal overdose.

In the morning, Panettiere woke up and put on makeup, he remarked, and the pair ate cereal together before he fell back asleep. Brian Hickerson remarked he woke up in the afternoon to Zach Hickerson knocking on his door so the trio could go to lunch, but upon going to wake up Panettiere, they identified her "crisscross applesauce, " face down and unresponsive on a sofa bed.

Brian Hickerson remarked he administered multiple cans of Narcan, a nasal spray that can reverse life-threatening opioid overdoses, but nothing changed. He informed his brother to call 911, and they kicked off CPR until emergency personnel arrived.

One of the brothers informed the deputy that Panettiere had a long history of drug, alcohol and nitrous oxide abuse.

According to The report additionally, a redacted name, assumed to be Brian Hickerson, was not aware of Panettiere using any illegal substances that day or the day prior, but noted that she was highly good at hiding them and that he had administered Narcan to her before. Hayden Panettiere's boyfriend detained, his brother arrested.

On Sept. 12, almost a month after the "Remember the Titans" actress' death, her boyfriend, Brian Hickerson, was briefly detained by police after a documented assault at Wild Wing Café in Greenville, South Carolina. The 38-year-old was among the "multiple patrons" detained in the alleged altercation but was afterwards issued at the scene with no charges.

Police additionally arrested his brother Zach Hickerson – who was reportedly "highly intoxicated" and "began yelling profanities in a public setting" – and afterwards booked him into the Greenville County Detention Center. He was published the after day after paying a $150 fine on Sept. 23, court records reviewed by USA TODAY Sept. 24 indicated. Zach Hickerson's case has since been disposed of. Brother of Hayden Panettiere's boyfriend resolves court case after arrest. Investigators continue to investigate source of fentanyl-laced pills. Questions still remain regarding the source of the fentanyl-laced pills.

Investigators with the DEA and other departments, from both Los Angeles and South Carolina, are focused on identifying what drugs contributed to her death and where those drugs came from, according to ABC News, citing unnamed sources.

Notably, the department has not commented on the state of the investigation, simply noting it is "active" and telling Greenville, South Carolina, station WYFF4 that "these cases are complex and take time to develop."

Contributing: Terry Benjamin II, Greenville News; Brendan Morrow, Sameen Chaudhry, KiMi Robinson, USA TODAY. Share your feedback to support improve our site!

In short, questions remain as details keep emerging in Hayden Panettiere death is the central thread here, and readers can expect follow-up reporting as the picture becomes clearer.